The health costs of smoking are clear, but the economic impact of tobacco often gets overlooked. While overall smoking rates have declined across the country, the pace of progress can be drastically slower, or nonexistent, depending on an individual’s socioeconomic status. Additionally, there are many challenges involved in identifying the costs – in dollars, disease, and death – associated with smoking that can be used in economic evaluations. Estimates on the costs and benefits associated with preventing or quitting smoking are needed to understand the potential economic impact of tobacco.